Light Sources for Neuroscience
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Combi-LED
Prizmatix Combi-LED is custom designed multi wavelength (up to 9 independent LED sources) High-Power Light-Engine. Combi-LED flexible design and spectra simulation tool enables production of fully customized sophisticated light source. Each LED channels features distinct Analog Input, for power control, and TTL input, for fast pulsing. Both inputs are Optically-Isolated. Computer control by common software packages like MetaMorph, LabVIEW, Matlab or others, API is available. The product available in 19” rack enclosure. The light delivery is by a liquid light guide providing excellent flat field homogeneous illumination. The wavelength switching time is within <5msec by the software and <5usec by TTL inputs.
Ultra High Power Collimated LED Sources & Neuroscience In-Vitro Toolkit
The UHP-T-LED Ultra-High Power Collimated LED is a powerful light source that can be used for fluorescence microscopy, neuroscience, and other scientific applications. The LED head comprises a LED chip with an aspheric collimator. The LED head also contains a shielded high-current driver to reduce RFI/EMI interference and enable fast TTL switching. The product can be used as a collimated, liquid light guide, or optical fiber-coupled LED light source along with all accessories (see below). Several UHP-T-LED product lines are available each optimized for different application (see below)
Accessories
Neuroscience Toolkit
Prizmatix Combi-LED is custom designed multi wavelength (up to 8 independent LED sources) High-Power Light-Engine. Combi-LED flexible design and spectra simulation tool enables production of fully customized sophisticated light source. Each LED channels features distinct Analog Input, for power control, and TTL input, for fast pulsing.
Both inputs are Optically-Isolated. Computer control by common software packages like MetaMorph, LabVIEW, Matlab or others, API is available. The product available in 19” rack enclosure. The light delivery is by a liquid light guide providing excellent flat field homogeneous illumination. The wavelength switching time is within <5msec by the software and <5usec by TTL inputs.
1. Ultra High Power Collimated LED
The UHP-T-LED Ultra-High Power Collimated LED is a powerful light source that can be used for fluorescence microscopy, neuroscience, and other scientific applications. The LED head comprises a LED chip with an aspheric collimator. The LED head also contains a shielded high-current driver to reduce RFI/EMI interference and enable fast TTL switching.
2. Beam Combiner
The Beam Combiner can join several discrete UHP-T-LEDs into one output beam, which can then be coupled to a microscope, liquid lightguide or an optical fiber. For increased versatility, additional optical filters can be installed at the input or the output ports of the Beam Combiner.
3. Fiber Coupler Adaptor
The output of UHP-T-LED or Beam Combiner can be easily changed from collimated output mode to fiber coupled mode by a Fiber Coupler Adaptor. The Fiber Coupler Adaptor is suitable for use with large core, high NA optical fibers (optimized for NA 0.5). The FCA enables connection of various fibers and use of UHP-T-LED system for application like in-situ activation.
4. Fiber Optics
Prizmatix offers a wide range of standard and customized multi-mode silica / polymer fibers as well as ferrules for optogenetics research. The Polymer Optical fibers are especially useful for neuroscience research as they are extremely flexible and virtually non breakable. The Polymer Fibers typically have high NA well suited for LED light transmission. Prizmatix offers many configurations of fibers including Armored fibers, Y-shaped fiber bundles and much more.
5. Rotary Joint
Prizmatix's Rotary Joint is specially designed for Optogenetics experiments with High NA detachable fibers equipped with FC connectors. The torque required for free movement is very low thus reducing the Rotary Joint's behavioral effect on free moving animals, making it suitable for even the smallest rodents. Prizmatix Rotary Joint can be used with single or multiple output fibers simultaneously, enabling concurrent delivery of light to separate areas of the brain without loss of power or brightness.
6. Beam Switcher
The Beam Switcher allows for simple combining of different light sources to same epi-fluorescent port or to split the light from wide-field illumination to fiber optic in-situ point activation. Typically Beam Switcher shall be used with Fiber Coupler Adaptor (FCA) ad optical fibers.
7. Filter Wheel
The ICHI LED can be equipped with a 6 positions filter wheel at the beam output. This accessory is particularly useful for ICHI-White light source. Prizmatix offers manual and motorized versions of the Filter Wheel.
8. Microscope Adaptors
The microscope adaptors enable easy connection of Prizmatix LED light sources to the most widely used microscope brands. Adaptors for epi-fluorescence ports of Nikon, Zeiss, Olympus and Leica microscopes as well as C-mount thread adaptor (1-32 UN 2A thread) are availible.
9. Liquid Light Guide Adaptor / Collimator
The output of ICHI LED or Beam Combiner can be easily changed from collimated output mode to light guide coupled mode. The Liquid Light Guide Adaptor (LLG-A) is suitable for use with standard high NA liquid light guides. The Liquid Light Guide Adaptors available for 3mm and for 5mm Light Guides. Same part can be used as fixed collimator on distal end of the liquid light guide. For microscopy applications preferably to use XYZ Collimator (see #11 below)
10. Liquid Light Guide
Prizmatix flexible 3mm or 5mm core liquid light-guide is ideal to conduct light from the large LED emitter to the microscope. The light output from Light Guide equipped with suitable collimator is highly homogeneous and provide flat field illumination.
11. Liquid Light Guide XYZ Collimator
The Prizmatix XYZ LLG collimator is an XY and Z adjustable collimator for Liquid Light Guide (LLG) with adaptor for the epi-illumination port of fluorescence microscopes. This collimator can be equipped with Nikon, Olympus, Zeiss or Leica adaptors.
13. Fiberoptic Collimator
Collimators are used to reduce the naturally diverging light emission from an optical fiber.
Prizmatix collimator is designed to collimate High NA fibers (up to 0.53), such as Hard Polymer Clad fibers and Polymer Optical Fibers (POFs).
14. Reference Photodiode
Reference photodiode is useful in order to monitor LED source power over time in experiments required exceptional stability over long time period. The photodiode signal can be used to normalize measurements done over long time period.
15. Single Dual Fiber
Prizmatix provides a full solution to the optogenetics in vivo and in vitro fiber optics. Made of silica or polymer fibers, the high NA fibers are assembled to fit any research set-up with various combinations of connectors, ferrules, core diameters and lengths.
17. Pulser / PulserPlus
Optogenetics Pulser / PulserPlus are programmable TTL pulse train generators for pulsing LEDs, lasers and shutters used in Optogenetics activation in neurophysiology and behavioral research. The Pulser device comes with user friendly Windows software that enables easy visual setup of numerous pulse train configurations.
ICHI Accessories
ICHI Reference Photodiode
Reference photodiode is useful in order to monitor LED source power over time in experiments required exceptional stability over long time period. The photodiode signal can be used to normalize measurements done over long time period. In applications requiring prolonged irradiation the reference photodiode can be used with UHPTLCC-02-STBL controller actively stabilize the output power.
